Senior Product Manager (Menlo Park, CA or Durham NC) - 4564

Company: GRAIL Inc
Location: Durham
Posted on: February 19, 2026

Job Description:

Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care. We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges. GRAIL is headquartered in the bay area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies. For more information, please visit grail.com As a Senior Software Product Manager, you will play a key role in defining priorities and requirements to continue to evolve our software platform leveraged for getting samples into the lab and results out to patients. This set of software capabilities drives a core of GRAIL’s business - converting specimens into insights which power improved patient outcomes. This is a hybrid role based in either Menlo Park, CA (moving to Sunnyvale, CA in Fall 2026) or Durham, NC . Our current flexible work arrangement policy requires that a minimum of 60%, or 24 hours, of your total work week be on-site. Your specific schedule, determined in collaboration with your manager, will align with team and business needs and could exceed the 60% requirement for the site. Responsibilities Develop and deliver on product roadmaps for GRAIL’s sample receipt, accessioning, and report review software platform, based on a deep understanding of user needs and business goals Build alignment among stakeholders and collaborating teams (Operations, Billing, Commercial, Software Engineering, Medical Affairs, Quality, etc.) Partner closely with Software Engineering, Program Management, and the Test Team to drive prioritization, execution, and delivery of high impact features and functionality based on business value and user needs Remove bottlenecks that directly impact our anti-cancer mission Write product and software requirements to guide software development Create and maintain processes for collecting and prioritizing feedback and requests from users Partner with Regulatory and Quality teams to support risk assessments, audits and software validation These responsibilities summarize the role’s primary responsibilities and are not an exhaustive list. They may change at the company’s discretion. Required Qualifications 5 years of experience in software product management BA/BS, Graduate degree, or equivalent work experience in life or physical sciences, engineering or computer science or equivalent Experience working with regulated products Excellent strategic, analytical, communication and presentation abilities. Demonstrated ability to: independently navigate and lead through ambiguity; guide without authority; negotiate scope, product features, and specifications with stakeholders and the development team Ability to ruthlessly prioritize, set goals and deliver results with an emphasis on quality, technical planning, and attention to detail Experience working in a fast-paced environment, leading complex strategic and operational initiatives, working through technical, operational, legal/regulatory, and business issues. Ability to prioritize, set goals and deliver results with a high emphasis on quality, technical planning, and attention to detail. Preferred Qualifications Experience in the development or utilization of software to support lab processes, workflow automation, or other high volume manufacturing processes is highly preferred Experience in healthcare, life sciences, diagnostics, or other regulated industries is highly preferred Experience working with AI tools is preferred The expected, full-time, annual base pay scale for this position is $136K-$180K. This role may be eligible for other forms of compensation, including an annual bonus and/or incentives, subject to the terms of the applicable plans and Company discretion. This range reflects a good-faith estimate of the range that the Company reasonably expects to pay for the position upon hire; the actual compensation offered may vary depending on factors such as the candidate’s qualifications. Employees in this role are also eligible for GRAIL’s comprehensive and competitive benefits package, offered in accordance with our applicable plans and policies. This package currently includes flexible time-off or vacation; a 401(k) retirement plan with employer match; medical, dental, and vision coverage; and carefully selected mindfulness programs. GRAIL is an equal employment opportunity employer, and we are committed to building a workplace where every individual can thrive, contribute, and grow. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, gender, gender identity, sexual orientation, age, disability, status as a protected veteran, , or any other class or characteristic protected by applicable federal, state, and local laws. Additionally, GRAIL will consider for employment qualified applicants with arrest and conviction records in a manner consistent with applicable law and provide reasonable accommodations to qualified individuals with disabilities. Please contact us at [email protected] if you require an accommodation to apply for an open position. GRAIL maintains a drug-free workplace. We welcome job-seekers from all backgrounds to join us!

Keywords: GRAIL Inc, Fayetteville , Senior Product Manager (Menlo Park, CA or Durham NC) - 4564, IT / Software / Systems , Durham, North Carolina